USES
Is used to treat aches and pains, headache, fever, and congestion associated with the flu, colds, allergies, and hay fever.

WHAT TO KNOW

Use caution when driving, operating machinery, or performing other hazardous activities. Acetaminophen and phenyltoloxamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking acetaminophen and phenyltoloxamine. Alcohol may also cause damage to your liver when taken with acetaminophen.

WHAT IS IT

Apagesic

Dolorex

Duogesic

Flextra DS

Genasec

Percogesic

BEFORE USING
Do not take this medication without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease. You may not be able to take acetaminophen.

Do not take acetaminophen and phenyltoloxamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very serious drug interaction could occur, leading to serious side effects.

MISSED DOSE
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

OVER DOSE
Seek emergency medical attention.

Symptoms of an acetaminophen and phenyltoloxamine overdose may include:

nausea

vomiting

diarrhea

abdominal pain

sweating

seizures

confusion

sedation

insomnia

tremor

hallucinations

an irregular heartbeat

SIDE EFFECTS
If you experience any of the following serious side effects, stop taking acetaminophen and phenyltoloxamine and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)

liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, or severe fatigue);

blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst, dizziness, or fainting)

Other, less serious side effects may be more likely to occur including:

dry eyes, nose, and mouth

drowsiness or dizziness

blurred vision

difficulty urinating

excitation in children

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

PRECAUTIONS
Before taking this medication, tell your doctor if you have:

liver disease

kidney disease

diabetes

glaucoma

difficulty urinating because of an enlarged prostate, a constricted bladder neck, or any other reason

a stenosing peptic (stomach) ulcer

high blood pressure or any type of heart disease or an overactive thyroid

You may not be able to take acetaminophen and phenyltoloxamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether acetaminophen and phenyltoloxamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Acetaminophen and phenyltoloxamine passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from acetaminophen and phenyltoloxamine. Read the package label for directions or consult your doctor or pharmacist before treating a child with this medication. Children are more susceptible than adults to the effects of medicines and may have unusual reactions.

DRUG INTERACTIONS
Do not take acetaminophen and phenyltoloxamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very serious drug interaction could occur, leading to serious side effects. Urine glucose tests may produce false results while you are taking acetaminophen. Talk to your doctor if you are diabetic and you notice changes in your glucose levels during therapy with acetaminophen and phenyltoloxamine. Do not take other over-the-counter cough, cold, allergy, diet, pain or sleep medicines while taking acetaminophen and phenyltoloxamine without first talking to your doctor. Other medications may also contain acetaminophen, phenyltoloxamine, or other similar drugs and you may accidentally take too much of these medicines. Acetaminophen and phenyltoloxamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if acetaminophen and phenyltoloxamine is taken with any of these medications. Drugs other than those listed here may also interact with acetaminophen and phenyltoloxamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.